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VOLUME 3 , ISSUE 3 ( July-September, 2020 ) > List of Articles

Original Article

Proposed Yoga Protocol Based on Glycemic Control, Insulin Resistance and Anthropometry-specified Parameters: A Retrospective Study on Clinically Euthyroid Type II Diabetics

Manoharan Mangalagowri, Rajendran Jayanthi, Abu R Srinivasan, Ananda B Bhavanani, Ramanathan Meena

Keywords : Asian Indian, Euthyroid, Insulin resistance, T2DM, WHO, Yoga,Anthropometry

Citation Information : Mangalagowri M, Jayanthi R, Srinivasan AR, Bhavanani AB, Meena R. Proposed Yoga Protocol Based on Glycemic Control, Insulin Resistance and Anthropometry-specified Parameters: A Retrospective Study on Clinically Euthyroid Type II Diabetics. 2020; 3 (3):107-114.

DOI: 10.5005/jp-journals-10082-02250

License: CC BY-NC 4.0

Published Online: 00-09-2020

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Background and objectives: Inclusion of yoga in the daily routine would favorably moderate glycemic control, alleviate insulin resistance (IR), besides reducing the risk of complications in people with long-standing diabetes and comorbidity. The body mass index (BMI) cut-off criteria are different as per the Asian Indian and WHO standards. Accordingly, overweight range of 23–24.9 in the Asian Indian category will fall under the nonobese category. Obese range of ≥25 BMI in the Asian Indian group will come under the overweight category as per the WHO standards. To devise a unique yoga protocol based on anthropometry and biochemical assessment, has been proposed with reference to specific parameters in insulin-resistant, clinically euthyroid type II diabetics with special reference to Asian Indian and WHO standards. Materials and methods: A retrospective study was conducted in the Department of Biochemistry with inputs from the diabetic clinic of a tertiary care teaching hospital as well as a designated center for yoga therapy, following acceptance from the research advisory committee. The study subjects were clinically euthyroid type II diabetics (both genders) in the age group 35–70 years who were on diabetic diet and oral hypoglycemic agents (OHAs). Data from clinically euthyroid type II diabetics (n = 101) (adult males and females in the age group 35–70) were utilized for the study. The Pearson correlation coefficient and multivariate analysis were enabled and p < 0.05 was considered significant. Results: Statistically significant associations were observed between IR (dependent variable) and other independent variables, namely HbA1c, TAG/HDL (surrogate marker of small dense LDL), and thyroid hormones. With reference to BMI, based on Asian Indian standards, TAG/HDL depicted association with homeostasis model assessment-Insulin resistance (HOMA-IR) (p = 0.011) and TSH was negatively associated with HbA1c (p = 0.027) in overweight; HbA1c and TSH exhibited positive association with p = 0.001 and 0.04, respectively, in obese as per the Asian Indian criteria for BMI. Keeping BMI as per the WHO, TAG/HDL (p = 0.008) in nonobese and in overweight HbA1c with p = 0.001 were associated with HOMA-IR. Significant association was not found in the obese subjects, as per the WHO standards. Conclusion: There is a need for a unique yoga protocol to address clinically euthyroid type II diabetics. Hitherto, such a protocol has not been developed, especially with reference to BMI, as per the Asian Indian and WHO standards. Practicing this proposed yoga protocol on the basis of anthropometry might prove beneficial in glycemic control, alleviating IR, besides reducing complications of type II diabetics in euthyroid population who may later be candidates for frank thyroid comorbidity.


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