SBV Journal of Basic, Clinical and Applied Health Science

Register      Login

VOLUME 3 , ISSUE 3 ( July-September, 2020 ) > List of Articles


Systemic Lupus Erythematosus in a Man with Unusual Combination of Multiple Antibodies: A Rare Presentation

Roshni Kakitha, Sreedevi Ambujam

Citation Information : Kakitha R, Ambujam S. Systemic Lupus Erythematosus in a Man with Unusual Combination of Multiple Antibodies: A Rare Presentation. 2020; 3 (3):131-132.

DOI: 10.5005/jp-journals-10082-02237

License: CC BY-NC 4.0

Published Online: 30-11-2020

Copyright Statement:  Copyright © 2020; The Author(s).


Systemic lupus erythematosus (SLE) is a connective tissue disorder involving multiple systems of the body, skin being one of the earliest systems to get involved. We report the case of a 29-year-old male patient, with acute vesicular malar rash and a host of positive antibodies, viz., ANA, anti-ds DNA, anti-Smith, APAbs, anti-U1RNP, and anti-histone. He also had low complement levels. Occurrence of SLE is rare in men. Presence of a variety of antibodies without the correlating systemic involvement is rarer still, making this a case worth reporting.

  1. Rook's Textbook of Dermatology, In: Griffiths C, Barker J, Bleiker T, Chalmers R, Creamer D 9th edn., Chichester, West Sussex, Hoboken, NJ: John Wiley and Sons Inc; 2016.
  2. Satoh M, Fritzler MJ, Chan EKL. Chapter 28—Antihistone and antispliceosome antibodies. In: Tsokos GC. Systemic Lupus Erythematosus. 2nd edn., Academic Press; 2021. pp. 237–247.
  3. Abu-Shakra M, Gladman DD, Urowitz MB, Farewell V. Anticardiolipin antibodies in systemic lupus erythematosus: clinical and laboratory correlations. Am J Med 1995;99(6):624–628. DOI: 10.1016/S0002-9343(99)80249-6.
  4. Ramos-Casals M, Campoamor MT, Chamorro A, Salvador G, Segura S, Botero JC, et al. Hypocomplementemia in systemic lupus erythematosus and primary antiphospholipid syndrome: prevalence and clinical significance in 667 patients. Lupus 2004;13(10):777–783. DOI: 10.1191/0961203304lu1080oa.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.