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VOLUME 3 , ISSUE 4 ( October-December, 2020 ) > List of Articles

Original Article

Assessment of Serum Electrolytes and Divalent Cation in Preeclampsia: A Comparative Study

Sathiya Ramasamy, Reeta Rajagambeeram, Ramesh Ramasamy, Sumathi Saravanan

Keywords : Electrolytes, Magnesium, Preeclampsia, South India

Citation Information : Ramasamy S, Rajagambeeram R, Ramasamy R, Saravanan S. Assessment of Serum Electrolytes and Divalent Cation in Preeclampsia: A Comparative Study. 2020; 3 (4):154-157.

DOI: 10.5005/jp-journals-10082-02268

License: CC BY-NC 4.0

Published Online: 09-02-2021

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Background and objective: Preeclampsia is one of the hypertensive disorders of pregnancy, which affects 8–10% of pregnancy and it is the leading cause of maternal and fetal morbidity and mortality. Due to the significant role of serum electrolyte and magnesium in blood pressure regulation, this study was conducted to evaluate its role in preeclampsia. Materials and methods: A total of 30 subjects were recruited according to ACOG guidelines 2013 and 30 normotensive pregnant women, who were aged between 18 years and 40 years, who had referred from the obstetrics and gynecology department. Initially, 2 mL of blood samples were obtained from all the subjects and the samples were analyzed for serum magnesium by the calmagite method and electrolytes by the ion-selective electrode. The paired t test-Wilcoxon signed-rank test was performed to find if there was a significant difference between the groups. A p value of <0.05 was considered statistically significant. Results: Elevated systolic, diastolic blood pressure and decreased sodium, potassium, and magnesium levels were found in preeclampsia patients compared to normotensive pregnant woman. Conclusion: A decrease in serum magnesium and electrolyte levels contributes to the development of preeclampsia by regulating blood pressure.


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