Efficacy of 2% Chitosan Mouthwash on Plaque Reduction in Comparison with 0.2% Chlorhexidine Mouthwash among Young Adults: A Triple-blinded Crossover Randomized Controlled Trial
Citation Information :
Baskaran NG, Murugaboopathy V, Gunasekaran V. Efficacy of 2% Chitosan Mouthwash on Plaque Reduction in Comparison with 0.2% Chlorhexidine Mouthwash among Young Adults: A Triple-blinded Crossover Randomized Controlled Trial. 2021; 4 (2):35-38.
Aim and objective: The purpose of this study was to assess the 2% chitosan mouthwash on plaque reduction in comparison with 0.2% chlorhexidine mouthwash among young adults in Puducherry.
Materials and methods: A triple-blinded crossover randomized controlled trial was conducted among 20 first-year dental students, residing at college hostel in Puducherry. The subjects were randomly allotted to two groups (group I: 2% chitosan mouthwash and group II: 0.2% chlorhexidine mouthwash) with 10 subjects in each group. The plaque index proposed by Silness and Loe in 1967 was used for the assessment of plaque accumulation at baseline and 1 week after using mouthwashes. After a washout period of 30 days, mouthwashes were exchanged between the two groups, and plaque index was recorded. Data were assessed using an independent t-test and paired t-test.
Results: A significant reduction in plaque index scores was observed from baseline to 1 week following intervention (p <0.05) in both the groups during both phases. However, there was no significant difference between the two groups in plaque reduction (p >0.05).
Conclusion: This study reveals that 2% chitosan mouthwash is as effective as 0.2% chlorhexidine mouthwash, thereby warranting the use of the chitosan mouthwash for managing patients who show side effects associated with chlorhexidine.
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