Efficacy of 2% Chitosan Mouthwash on Plaque Reduction in Comparison with 0.2% Chlorhexidine Mouthwash among Young Adults: A Triple-blinded Crossover Randomized Controlled Trial

Nivetha Girija Baskaran; Anusha Divvi; Senthil Murugappan; Shivashankar Kengadaran; Vikneshan Murugaboopathy; Vidhya Gunasekaran

doi:10.5005/jp-journals-10082-03108

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Efficacy of 2% Chitosan Mouthwash on Plaque Reduction in Comparison with 0.2% Chlorhexidine Mouthwash among Young Adults: A Triple-blinded Crossover Randomized Controlled Trial

Nivetha Girija Baskaran, Anusha Divvi, Senthil Murugappan, Shivashankar Kengadaran, Vikneshan Murugaboopathy, Vidhya Gunasekaran

Keywords : Chitosan, CHX, Gingivitis, Prevention

Citation Information : Baskaran NG, Divvi A, Murugappan S, Kengadaran S, Murugaboopathy V, Gunasekaran V. Efficacy of 2% Chitosan Mouthwash on Plaque Reduction in Comparison with 0.2% Chlorhexidine Mouthwash among Young Adults: A Triple-blinded Crossover Randomized Controlled Trial. 2021; 4 (2):35-38.

DOI: 10.5005/jp-journals-10082-03108

License: CC BY-NC 4.0

Published Online: 27-07-2021

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Abstract

Aim and objective: The purpose of this study was to assess the 2% chitosan mouthwash on plaque reduction in comparison with 0.2% chlorhexidine mouthwash among young adults in Puducherry. Materials and methods: A triple-blinded crossover randomized controlled trial was conducted among 20 first-year dental students, residing at college hostel in Puducherry. The subjects were randomly allotted to two groups (group I: 2% chitosan mouthwash and group II: 0.2% chlorhexidine mouthwash) with 10 subjects in each group. The plaque index proposed by Silness and Loe in 1967 was used for the assessment of plaque accumulation at baseline and 1 week after using mouthwashes. After a washout period of 30 days, mouthwashes were exchanged between the two groups, and plaque index was recorded. Data were assessed using an independent t-test and paired t-test. Results: A significant reduction in plaque index scores was observed from baseline to 1 week following intervention (p <0.05) in both the groups during both phases. However, there was no significant difference between the two groups in plaque reduction (p >0.05). Conclusion: This study reveals that 2% chitosan mouthwash is as effective as 0.2% chlorhexidine mouthwash, thereby warranting the use of the chitosan mouthwash for managing patients who show side effects associated with chlorhexidine.

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