Background: Peptic ulcer is one of the most common diseases among Indian population. It can lead to several complications such as perforation, bleeding, etc., which require prompt diagnosis and treatment to reduce mortality and morbidity. This study aims to stratify the risk in patients with peptic ulcer perforation (PULP) using the PULP score. Materials and methods: It is a single-center prospective observational study conducted for a period of 1½ years with data collection for 1 year and analysis and write-up for 6 months (June 2017–November 2018). The study involved patients who underwent emergency surgery for perforated peptic ulcer (PPU). The PULP score and the perforation operation time interval are applied to all patients and their outcome is studied. Results: A total of 71 patients were included in the study; 6 patients died with a mortality rate of 8.5%. The mean PULP score in patients who expired was found to be 9. Complications occurred in 21 patients and the most common complication being the postoperative wound-site infection and acute respiratory distress syndrome (ARDS), which were significantly found in patients with the perforation operation time interval more than 24 hours. Conclusion: The PULP score is a reliable predictor of morbidity and mortality in patients who were operated for PULPs. The perforation operation time interval is a significant factor in predicting the mortality, complications, and the duration of hospital stay.
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