Citation Information :
Mithunkul S, Subramaniyan V, Shankar S, Paul J, Balaganesan H, Punchiry A. Correlation of Duplex Ultrasound and Biochemical Parameters in Diabetic Nephropathy: A Narrative Review. 2022; 5 (3):66-68.
Diabetic nephropathy (DN) is a chronic microvascular complication of diabetic mellitus. Progressive loss of kidney function can lead to end-stage renal disease (ESRD). Diabetic nephropathy can be detected and managed early, which can help to prevent or postpone the development of ESRD. Duplex ultrasound can be used to quantify renal characteristics such as length, echogenicity, parenchymal thickness, and resistive index (RI), which could help in the early diagnosis of DN. The purpose of this article was to study the correlation of duplex ultrasound findings and biochemical parameters in diabetic nephropathic patients. A progressive increase in the renal RI, derangement of renal sonomorphological parameters, and biochemical parameters were found with advancing DN. Similar studies have shown this relationship which can be used for early detection of DN which helps to reduce morbidity to great extent.
Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27(5):1047–1053. DOI: 10.2337/diacare.27.5.1047.
Ramachandran A, Snehalatha C, Shetty AS, Nanditha A. Trends in prevalence of diabetes in Asian countries. World J Diabetes 2012;3(6):110. DOI: 10.4239/wjd.v3.i6.110.
Trikkalinou A, Papazafiropoulou AK, Melidonis A. Type 2 diabetes and quality of life. World J Diabetes 2017;8(4):120. DOI: 10.4239/wjd.v8.i4.120.
Van Buren PN, Toto R. Hypertension in diabetic nephropathy: epidemiology, mechanisms, and management. Adv Chronic Kidney Dis 2011;18(1):28–41. DOI: 10.1053/j.ackd.2010.10.003.
Koroshi A. Microalbuminuria, is it so important? Hippokratia 2007;11(3):105. PMID: 19582202.
Soldo D, Brkljacic B, Bozikov V, Drinkovic I, Hauser M. Diabetic nephropathy: comparison of conventional and duplex Doppler ultrasonographic findings. Acta Radiol 1997;38(2):296–302. DOI: 10.1080/02841859709172067.
Shumway JT, Gambert SR. Diabetic nephropathy-pathophysiology and management. Int Urol Nephrol 2002;34(2):257–264. DOI: 10.1023/a:1023244829975.
Fiorini F, Barozzi L. The role of ultrasonography in the study of medical nephropathy. J Ultrasound 2007;10(4):161–167. DOI: 10.1016/j.jus.2007.09.001.
Elshweehy S, Mohammed H, Osama S. Role of duplex doppler ultrasound in evaluation of patients with diabetic nephropathy. Sci J Al-Azhar Med Fac Girls-2020;4(3):456–462. DOI: 10.4103/sjamf.sjamf_69_20.
Gopalakrishnan SS, Balasubramaniam P, Reddy KS. Role of ultrasound and colour doppler in diabetic nephropathy-correlation with biochemical parameters. Int J Anat Radiol Surg 2019;8:RO31. DOI: 10.7860/IJARS/2019/41532:2503.
Ahmed S, Bughio S, Hassan M, Lal S, Ali M. Role of ultrasound in the diagnosis of chronic kidney disease and its correlation with serum creatinine level. Cureus 2019;11(3):e4241. DOI: 10.7759/cureus.4241.
Maksoud AA, Sharara SM, Nanda A, Khouzam RN. The renal resistive index as a new complementary tool to predict microvascular diabetic complications in children and adolescents: a groundbreaking finding. Ann Transl Med 2019;7(17):422. DOI: 10.21037/atm.2019.08.65.
Shaw M, Bhagat S, Panda BB, Nisa S, Das B, Panda A. Diabetic nephropathy: ultrasound, color doppler and biochemical correlation-a 2-year study. JMSCR 2016;4(8):12025–12034. DOI: 10.18535/jmscr/v4i8.58.
Siddappa JK, Singla S, Mohammed Al Ameen SC, Kumar N. Correlation of ultrasonographic parameters with serum creatinine in chronic kidney disease. J Clin Imaging Sci 2013;3:28. DOI: 10.4103/2156-7514.114809.
Mancini M, Masulli M, Liuzzi R, Mainenti PP, Ragucci M, Maurea S, et al. Renal duplex sonographic evaluation of type 2 diabetic patients. J Ultrasound Med 2013;32(6):1033–1040. DOI: 10.7863/ultra.32.6.1033.
Sperandeo M, Varriale A, D'Amico G, Sperandeo G, Piattelli ML, De Cata A, et al. Intrarenal resistive index in patients with type 2 diabetes mellitus with and without microalbuminuria. Eur J Inflammation 2007;5(2):103–110. DOI: 10.1177/1721727X0700500207.
Casadei A, Floreani M, Fanolla A, Gaspa U, Marchesi M. Renal Doppler color ultrasonography in the study of diabetic nephropathy. Arch Ital Urol Androl 2000;72(4):205–210. PMID: 11221038.