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VOLUME 5 , ISSUE 4 ( October-December, 2022 ) > List of Articles


A Rare Case of Recurrent Pseudomyxomatous Peritonei Presenting as Peritoneo-cutaneous Fistula: A Case Report

VC Maruduraj, Muralidharan Gopalan, A Naren Kumar, Fazil Navidh, Sharan Bhooshan, Mohana Priya

Keywords : Mucinous, Peritonei, Pseudomyxoma

Citation Information : Maruduraj V, Gopalan M, Kumar AN, Navidh F, Bhooshan S, Priya M. A Rare Case of Recurrent Pseudomyxomatous Peritonei Presenting as Peritoneo-cutaneous Fistula: A Case Report. 2022; 5 (4):92-96.

DOI: 10.5005/jp-journals-10082-03154

License: CC BY-NC 4.0

Published Online: 18-08-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Pseudomyxoma peritonei (PMP) is a rare disorder, characterized by diffuse intra-abdominal gelatinous contents, the so-called “jelly belly like content,” with mucinous implants on the peritoneal surface. We report a case of an 84-year-old female, with a history of abdominal diffuse swelling for 7 years and yellow jelly-like discharge below the umbilicus. Abdominal ultrasonography and CT scan of the abdomen showed the jelly-like collection in the entire abdomen and pelvis extending through the subcutaneous plane. Laparotomy showed cheese burst defect in linea alba and yellow jelly-like mucinous fluid. The histological study revealed mucinous cells. The patient had a good postoperative performance status. Pseudomyxomatous peritonei describes the peritoneal dissemination of mucus-producing tumors, most frequently from the appendix but also occurs in the small and large bowel, stomach, pancreas, lung, breast, gallbladder, fallopian tubes, and ovaries. Due to its aggressive behavior, often discovered incidentally at a relatively advanced stage during screening for other medical concerns. PMP demands consideration as a ‘borderline malignancy’ with a differential prognosis based on the site of origin.

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  1. Ansari N, Chandrakumaran K, Dayal S, Mohamed F, Cecil TD, Moran BJ. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in 1000 patients with perforated appendiceal epithelial tumours. Eur J Surg Oncol 2016;42(7):1035–1041. DOI: 10.1016/j.ejso.2016.03.017.
  2. Chua TC, Yan TD, Smigielski ME, Zhu KJ, Ng KM, Zhao J, et al. Long-term survival in patients with pseudomyxoma peritonei treated with cytoreductive surgery and perioperative intraperitoneal chemotherapy: 10 years of experience from a single institution. Ann Surg Oncol 2009;16(7):1903–1911. DOI: 10.1245/s10434-009-0341-8.
  3. Ronnett BM, Seidman JD. Mucinous tumors arising in ovarian mature cystic teratomas: relationship to the clinical syndrome of pseudomyxoma peritonei. Am J Surg Pathol 2003;27(5):650–657. DOI: 10.1097/00000478-200305000-00008.
  4. Mukherjee A, Parvaiz A, Cecil TD, Moran BJ. Pseudomyxoma peritonei usually originates from the appendix: a review of the evidence. Eur J Gynaecol Oncol 2004;25(4):411–414. PMID: 15285293.
  5. de Bree E, Witkamp A, Van De Vijver M, Zoetmulde F. Unusual origins of pseudomyxoma peritonei. J Surg Oncol 2000;75(4):270–274. DOI: 10.1002/1096-9098(200012)75:4<270::aid-jso9>;2-v.
  6. Werth R. Pseudomyxoma peritonei. Arch Gynaecol 1884;24:100–118. DOI: 10.1007/BF01837425.
  7. Li C, Kanthan R, Kanthan SC. Pseudomyxoma peritonei—a revisit: report of 2 cases and literature review. World J Surg Oncol 2006;4:60. DOI: 10.1186/1477-7819-4-60.
  8. Ronnett BM, Yan H, Kurman RJ, Shmookler BM, Wu L, Sugarbaker PH. Patients with pseudomyxoma peritonei associated with disseminated peritoneal adenomucinosis have a significantly more favorable prognosis than patients with peritoneal mucinous carcinomatosis. Cancer 2001;92(1):85–91. DOI: 10.1002/1097-0142(20010701)92:1<85::aid-cncr1295>;2-r.
  9. Pandey A, Mishra AK. Pseudomyxoma peritonei: disseminated peritoneal adenomucinosis variant. BMJ Case Rep 2011;2011: bcr.07.2010.3181. DOI: 10.1136/bcr.07.2010.3181.
  10. Singh D, Gilbert S, Natrajan S, Subramanian P, Kandasamy S. Pseudomyxoma pleurii—a case report with clinicopathology and management of rare clinical presentation. Indian J Immunol Respir Med 2016;1(2):40–42.
  11. Lang H, Jahne J, Flemming P, Meyer HJ, Pichlmayr R. Pseudomyxoma peritonei of appendiceal origin—a report of seven cases and a review of published reports. Eur J Surg 1995;161(5):355–360. PMID: 7662781.
  12. Limber GK, King RE, Silverberg SG. Pseudomyxoma peritonaei: a report of ten cases. Ann Surg 1973;178(5):587–593. DOI: 10.1097/00000658-197311000-00006.
  13. Qu ZB, Liu LX. Management of pseudomyxoma peritonei. World J Gastroenterol 2006;12(38):6124–6127. DOI: 10.3748/wjg.v12.i38.6124.
  14. Ioannidis O, Cheva A, Paraskevas G, Papadimitriou N, Konstantara A, Chatzopoulos S, et al. Pseudomyxoma retroperitonei: report of 2 cases and review of the literature. Rev Esp Enferm Dig 2012;104(5):268–275. DOI: 10.4321/s1130-01082012000500009.
  15. Sugarbaker PH. Pseudomyxoma peritonei. A cancer whose biology is characterized by a redistribution phenomenon. Ann Surg 1994;219(2):109–111. DOI: 10.1097/00000658-199402000-00001.
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