Background: Septoplasty is one of the most common procedures performed by otorhinolaryngologists. Nasal packs are placed following nasal surgery to arrest hemorrhage, prevent septal hematoma formation, and prevent postoperative adhesion formation. Many different forms of nasal packing materials have been used nowadays. The objective of this study was if to find out if nasal packing has any direct effect on postoperative complications of surgery for deviated nasal septum. Materials and methods: A prospective study was conducted among 40 patients in a tertiary care center for 18 months who underwent septal surgery in the department of otorhinolaryngology. Patients between the ages of 18 and 50 who underwent septal surgery were included. The subjects were divided into two groups: group I received a conventional nasal pack, and group II received Merocel postoperatively. Selected subjects were assessed first, second, and fourth weeks postoperatively, for any postoperative complications. Results: It was observed that group I had more synechiae and hematoma formation than group II. Conclusion: The conventional and Merocel packs were both effective packs. The Merocel pack is better in terms of minimizing the risk of postoperative complications.