Citation Information :
Shah T, Muthusamy R, Gangadharan RP. A Prospective Cohort Study to Record the Early Complications in Late Preterm Neonates and Maternal Factors Affecting Preterm Deliveries in a Tertiary Health Center. 2023; 6 (4):69-72.
Introduction: Late preterm newborns are at a higher risk of morbidity as compared to term infants, and as a result, they require additional attention and care during their early neonatal period in order to prevent probable complications. Late preterm infants are defined as those newborns born between 34 weeks and 36 weeks and six days of gestation. They do not acquire the significant and chronic illnesses that are commonly seen in infants born before 34 weeks of gestation. Late preterm babies are typically recognized and treated as though they are term babies and they develop issues during their initial days of life.
Methodology: This is a prospective cohort study conducted among newborns born during the study period of 18 months in a tertiary health center and their outcomes were studied. The newborns were observed and the general condition of the newborns was monitored during the initial 5 days of life in the hospital. Observation of common maternal factors leading to preterm births was also noted.
Results: In our study, the mean baby weight was recorded as 2.57 ± 0.55. Among the preterm neonates, only 66% didn't have any complication, and 34% developed complications. In the preterm group, among mothers 16% had diabetes, 13% had hypertension and 5% had primary rupture of members (PROM). We also noticed that birth weight, and baby weight for diabetic mothers was significant in the preterm group, and hypoglycemia, hypothermia, hyperbilirubinemia, respiratory distress, and feeding difficulty were found to be statistically significant and the risk factor and gestational age were statistically significant. (p-value < 0.001).
Discussion and conclusion: We conclude that infants who are late preterm are more likely to experience various neonatal complications. The majority of preterm newborns delivered at secondary-care institutions are late preterm neonates. Hospitalizations for birth and morbidity are important risks for them. Regardless of their physical characteristics, late preterm infants should get the same level of medical care as other pre-terms.
Teune MJ, Bakhuizen S, Bannerman CG, Opmeer BC, Van Kaam AH, Van Wassenaer AG, et al. A systematic review of severe morbidity in infants born late preterm. Am J Obstet Gynecol 2011;205(4):374.e1–e9. DOI: 10.1016/j.ajog.2011.07.015.
Engle WA, Tomashek KM, Wallman C, Committee on Fetus and Newborn, American Academy of Pediatrics. “Late-preterm” infants: A population at risk. Pediatrics 2007;120(6):1390–1401. DOI: 10.1542/peds.2007-2952.
Blencowe H, Cousens S, Chou D, Oestergaard M, Say L, Moller AB, et al. Born too soon: The global epidemiology of 15 million preterm births. Reprod health 2013;10(Suppl 1):S2. DOI: 10.1186/1742-4755-10-S1-S2.
Darcy AE. Complications of the late preterm infant. J Perinat Neonatal Nurs 2009;23(1):78–86. DOI: 10.1097/JPN.0b013e31819685b6.
Loftin RW, Habli M, Snyder CC, Cormier CM, Lewis DF, DeFranco EA. Late preterm birth. Rev Obstet Gynecol 2010;3(1):10–19. PMID: 20508778.
Mathews TJ, Hamilton BE. Mean age of mothers is on the Rise: United States, 2000–2014. NCHS Data Brief 2016;(232):1–8. PMID: 26828319.
Edagotti G, Ulli R, Korrapolu HB, Pedada R. Morbidity and mortality profile of late pre-terms in comparison to term newborns at a Tertiary Care Centre in Vijayawada - An observational study. J Evid Based Med Healthc 2021;8(42):3625–3632. DOI: 10.18410/jebmh/2021/65.
Yanit KE, Snowden JM, Cheng YW, Caughey AB. The impact of chronic hypertension and pregestational diabetes on pregnancy outcomes. Am J Obstet Gynecol 2012;207(4):333.e1–e6. DOI: 10.1016/j.ajog.2012.06.066.
Ylilehto E, Palomäki O, Korhonen P, Huhtala H, Uotila J. Impact of mode of delivery on perinatal outcome in moderately and late preterm twin birth. Int J Gynaecol Obstet 2021;153(1):106–112. DOI: 10.1002/ijgo.13418.
Araújo BF, Zatti H, Madi JM, Coelho MB, Olmi FB, Canabarro CT. Analysis of neonatal morbidity and mortality in late-preterm newborn infants. J Paediatr (Rio.J) 2012;88(3):259–266. DOI: 10.2223/jped.2196.
Rather GN, Jan M, Rafiq W, Gattoo I, Hussain SQ, Latief M. Morbidity and mortality pattern in late preterm infants at a Tertiary Care Hospital in Jammu & Kashmir, Northern India. J Clin Diagn Res 2015;9(12):SC01–SC04. DOI: 10.7860/JCDR/2015/16294.6916.
Wagh AS, Jain N. Comparison of neonatal morbidities of late preterm with term born babies. JPBMS 2012;15(9):1–5.
Sahana, Adarsh E, Sunil, Rajanish, Sreekrishna. Short term outcome of late preterms. IJAMS 2014;3(1):205–211.
Mally PV, Bailey S, Hendricks-Muñoz KD. Clinical issues in the management of late preterm infants. Curr Probl Pediatr Adolesc Health Care 2010;40(9):218–233. DOI: 10.1016/j.cppeds.2010.07.005.
Mank A, van Zanten HA, Meyer MP, Pauws S, Lopriore E, Te Pas AB. Hypothermia in preterm infants in the first hours after birth: Occurrence, course and risk factors. PLoS One 11(11):e0164817. DOI: https://doi.org/10.1371/journal.pone.0164817.
Khowaja WH, Leghari AL, Hussain AS, Ariff S, Khan IA. Frequency and early complications of late preterm infants: A descriptive analysis from two secondary-care hospitals of Karachi. Cureus 2019;11(9):e5789. DOI: 10.7759/cureus.5789.
Singh S, Seth A, Dey M, Maji D. Maternal factors associated with late preterm births. International Journal of Contemporary Medical Research 2016;3(9):2612–2616. ISSN (Online): 2393-915X.